Commuting between Golgi cisternae—Mind the GAP!
نویسندگان
چکیده
منابع مشابه
Almost Commuting Unitaries with Spectral Gap Are near Commuting Unitaries
Let Mn be the collection of n×n complex matrices equipped with operator norm. Suppose U, V ∈ Mn are two unitary matrices, each possessing a gap larger than ∆ in their spectrum, which satisfy ‖UV −V U‖ ≤ ǫ. Then it is shown that there are two unitary operators X and Y satisfying XY −Y X = 0 and ‖U−X‖+‖V −Y ‖ ≤ E(∆/ǫ) “ ǫ ∆2 ” 1 6 , where E(x) is a function growing slower than x 1 k for any posit...
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Golgins play diverse roles in regulating the structure and function of the Golgi. The yeast golgin Imh1p is targeted to the trans-Golgi network (TGN) through interaction of its GRIP domain with GTP-bound Arl1p. Recycling of Arl1p and Imh1p to the cytosol requires the hydrolysis of GTP bound to Arl1p; however, the point at which GTP hydrolysis occurs remains unknown. Here, we report that self-in...
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In eukaryotic cells, secretion is achieved by vesicular transport. Fusion of such vesicles with the correct target compartment relies on SNARE proteins on both vesicle (v-SNARE) and the target membranes (t-SNARE). At present it is not clear how v-SNAREs are incorporated into transport vesicles. Here, we show that binding of ADP-ribosylation factor (ARF)-GTPase-activating protein (GAP) to ER-Gol...
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15 صفحه اولRobustness effect of gap junctions between Golgi cells on cerebellar cortex oscillations
BACKGROUND Previous one-dimensional network modeling of the cerebellar granular layer has been successfully linked with a range of cerebellar cortex oscillations observed in vivo. However, the recent discovery of gap junctions between Golgi cells (GoCs), which may cause oscillations by themselves, has raised the question of how gap-junction coupling affects GoC and granular-layer oscillations. ...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
سال: 2005
ISSN: 0167-4889
DOI: 10.1016/j.bbamcr.2005.05.003